Scientist – In Vivo
Keros Therapeutics is a clinical-stage biopharmaceutical company developing novel therapeutics that target the TGF-β superfamily. We are seeking a motivated PhD scientist to join our growing research group and contribute to the development of novel therapeutics, with the goal of delivering medicines that modulate TGF-β signaling for the treatment of disorders with high unmet medical need.
The successful candidate will be an integral member of a team to help expand on our current portfolio and to develop novel therapeutics that treat rare blood disorders. This position will primarily involve translational research in hematology and iron metabolism but may also focus on aspects of muscle and bone biology.
- Design, plan, and execute in vivo pharmacology studies to evaluate efficacy, pharmacokinetics, pharmacodynamics, tolerability, and mechanism of action of drug candidates
- Perform in vivo analysis to help broaden our understanding of how our therapeutic leads mechanistically mediate their biological actions.
- Work with and manage external research at CROs.
- Analyze and present scientific data, engage colleagues in cross-disciplinary scientific discussion, and stay abreast of relevant scientific literature
- Aid in the training and mentoring of junior staff.
- PhD with 2-5 years of biomedical research experience, industry experience is a plus
- Expertise in working with rodent models in vivo
- Proficient in animal handling, dosing (IV, IP), blood collection, and tissue harvesting
- Experience with multiple molecular techniques (cell culture, ELISA, PCR, real-time PCR, western blot, etc.) is highly desirable
- The position requires excellent written and verbal communication skills and the ability to work effectively both independently and as part of multi-disciplinary team
- Must be a scientifically motivated self-starter, capable of independently conceiving, conducting, and critically analyzing his/her own innovative research with minimal supervision
- Strong presentation skills, communication, and the ability to work in a fast-paced and team-oriented environment will also be vital
- Demonstrated understanding of blood biology is desirable
Interested applicants can contact Martin Fisher, Associate Director of Research, Martin@Kerostx.com.
posted: January 11, 2021